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Mendelian Randomization to Identify Causal Links Using Genetic Associations​

Speaker: Sarah Gagliano Taliun

In this seminar we will describe the concept of Mendelian randomization and how to carry out this study design through the use of examples.

Learning objectives:

  1. Describe the concept of a Mendelian randomization study to the general public

  2. Understand the appropriate contexts for using Mendelian randomization

  3. List the assumptions central to Mendelian randomization and interpret results

About the Speaker:

Bio: Sarah Gagliano Taliun is an FRQS Junior 2 Assistant Professor at the Departments of medicine and neurosciences at the Université de Montréal. She leads a computational research group located at the Research Centre of the Montreal Heart Institute. Dr. Gagliano Taliun completed her PhD at the University of Toronto, and a postdoctoral fellowship at the University of Michigan before starting her own lab in Montreal in late 2020. Her research group uses computational tools and approaches to identify and better understand genetic factors contributing to complex human traits, primarily neurodegenerative disorders.

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